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阮文科

[发表时间]:2023-01-01 [浏览次数]:

阮文科,2003年进入北京农学院工作,预防兽医学博士,毕业于中国农业大学动物医学院,皇冠集团99442登录入口动物医学系副教授,硕士生导师。


研究领域为动物微生物学与免疫学。目前的主要研究方向为禽的固有免疫应答分子与病原之间的相互作用机理与抗感染免疫机理。目前主持完成国家自然科学基金面上项目1项、北京自然科学基金面上项目1项、北京市教委科研计划面上项目1项等。主要讲授动物免疫学、动物微生物学、生物制品学、禽病学等课程。获得北京市教委青年拔尖人才项目和市委组织部优秀人才项目资助。


代表性成果:


1Peng Wang, Xinze Liu, Qi Li, Jue Wang, Wenke Ruan. Proteomic analyses identify intracellular targets for Japanese encephalitis virus nonstructural protein 1 (NS1). Virus Res, 2021 Jun 24;302:198495. doi: 10.1016/j.virusres.2021.198495. Corresponding author

2Jinyan Zhu, Shuang Xu, Xueyan Li, Jue Wang, Yueqi Jiang, Weichen Hu, Wenke Ruan,

Infectious Bronchitis Virus Inhibits Activation of the TLR7 Pathway, but Not the TLR3 Pathway. Arch Virol, 2020 Jun 10;1-7.doi:10.1007/s00705-020-04690-8.  Corresponding author

3Peng Wang, Jinyan Zhu, Xinze Liu, Jiaojiao Guo, Xuejia Gu & Wenke RuanIsolation and recombinant analysis of variants of porcine epidemic diarrhea virus strains from Beijing, China. VirusDis. DOI 10.1007/s13337-019-00513-w1, 2019. Corresponding author

4WenKeRuanJian AnYanhuaWu, Polymorphisms of chicken TLR3 and 7 in different breeds, PLoS ONE 2015.10(3): e0119967. doi:10.1371/journal. pone.0119967. Corresponding author

5WenkeRuan, Yanhua Wu, Jian An, and ShijinZheng, Polymorphisms of chicken Toll-like receptors 4, 15, and 21 in different breeds, Poultry Science, 91, 2512-2516, 2012. Corresponding author.

6Yanhua Wu, WenkeRuan, Defeng Cui, and Huanrong li, Identification of a toll-like receptor1 in guinea fowl (Agelastesniger), Biochemical genetics, 50, 702716, 2012. Corresponding author.

7WenkeRuan, Yanhua Wu, Jian An, Dengfeng Cui, Huanrong Li, and shijunZheng, Toll-like receptor 2 type 1 and type 2 polymorphisms in different chicken breeds, Poultry Science, 91, 101-106. 2012. First Author.

8WenkeRuan, Yanhua Wu, and ShijunZheng, Different genetic patterns in avian Toll-like receptor (TLR)5 genes, Molecular Biology Reports, 39, 3419-3426, 2012, First Author.

9WenkeRuan and ShijunZheng, Polymorphisms of chicken toll-like receptor 1 type 1 and type 2 in different breeds, Poultry Science, 90, 1941-1947, 2011. First Author.

10国家发明专利:阮文科,郭娇娇,阮莹钰,张建军,谷学佳、徐双,用于检测PEDV变异株抗体的抗原及方法和试剂盒,2016.7.13 中国, ZL 2016 1 0552724.6

11、国家发明专利:阮文科,郭娇娇,王真,吴艳花,崔德凤,小片段gG抗原及其在检测伪狂犬病毒gG抗体中的应用,2015.9.15,中国,ZL 2015 1 0587831.8

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